ABSTRACT — Transverse maxillomandibular discrepancies need to be diagnosed early to achieve harmonious growth and allow the dentition to develop under the best possible conditions. The absence of treatment may generate skeletal asymmetries and/or temporomandibular joint dysfunctions. Late treatment can require surgical-orthodontic care; dental-alveolar compensations for malocclusion may also need to be performed. General practitioners, pediatric dentists and orthodontists thus play an essential role in the prevention phase. Accurate diagnosis and informed choice of treatment options allow to effective manage these types of malocclusion.