Oral condyloma acuminatum Benign epithelial tumor - ROS - 2017 - Tome 46 - N°2

GENERAL FEATURES
Condyloma acuminatum is defined as a benign epithelial tumor classified among sexually transmitted infections. In the majority of the cases, the human papillomavirus (HPV = human papillomavirus in international nomenclature) is at the cause of this lesion.

HPV is a virus with non-enveloped DNA, very resistant to chlorinated agents and to temperature variations. They are listed according to their cutaneous or mucous tropism and according to their oncogenic potential. The infections they provoke are very frequent due to the important risk of contagiousness. As a consequence, the majority of sexually active adults risk to be contaminated at some point in their life (Dalstein et al., 2006). Viruses responsible for condylomas are in 90% of the cases the mucous HPV type 6 and 11 said to be low risk tumors because the lesions do not theoretically evolve towards a cancer.

The viral transmission is usually made by direct sexual contact. The virus penetrates into the epithelium through a micro wound, spreads from cell to cell in the basal layer and virions are released during desquamation. The infectious agent can also be transmitted through water, through clothing and linen, through gloves or soiled material. The self- and the hetero-inoculation by hand are also possible. Indeed the viral concordance between genital and fingertip samplings is often considerable (Aubin 2006).

Agenda